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An autologous stem cell transplant uses healthy blood stem cells from your own body to replace your diseased or damaged bone marrow. An autologous stem cell transplant is also called an autologous bone marrow transplant.
Using cells from your own body during your stem cell transplant offers some advantages over stem cells from a donor. For example, you don't need to worry about incompatibility between the donor's cells and your own cells if you have an autologous stem cell transplant.
An autologous stem cell transplant might be an option if your body is producing enough healthy bone marrow cells. Those cells can be collected, frozen and stored for later use.
Autologous stem cell transplants are typically used in people who need to undergo high doses of chemotherapy and radiation to cure their diseases. These treatments are likely to damage the bone marrow. An autologous stem cell transplant helps to replace the damaged bone marrow.
An autologous stem cell transplant is most often used to treat:
Undergoing an autologous stem cell transplant involves:
Filtering stem cells from your blood (apheresis). For stem cell collection, a needle is inserted into a vein in your arm to draw out your blood. A machine filters out the stem cells and the rest of your blood is returned to your body.
A preservative is added to your stem cells and then they're frozen and stored for later use.
Undergoing high doses of cancer treatment (conditioning). During the conditioning process, you'll receive high doses of chemotherapy or radiation therapy — or sometimes both treatments — to kill your cancer cells. Which treatment you undergo depends on your disease and your particular situation.
The cancer treatments used during the conditioning process carry a risk of side effects. Talk with your doctor about what you can expect from your treatment.
After your autologous stem cell transplant, you'll remain under close medical care. You'll meet with your care team frequently to watch for side effects and to monitor your body's response to the transplant.
Last Updated Oct 5, 2019