Hirschsprung's disease involves missing nerve cells in the muscles of part or all of the large intestine (colon). Present at birth, it causes difficulty passing stool.
The main symptom is a newborn's failure to have a bowel movement within 48 hours after birth. Other symptoms include a swollen belly and vomiting.
Surgery is needed to bypass the affected part of the colon or remove it entirely.
Last Updated Jun 13, 2017