Retinal diseases

Overview

Retinal diseases vary widely, but most of them cause visual symptoms. Retinal diseases can affect any part of your retina, a thin layer of tissue on the inside back wall of your eye.

The retina contains millions of light-sensitive cells (rods and cones) and other nerve cells that receive and organize visual information. Your retina sends this information to your brain through your optic nerve, enabling you to see.

Treatment is available for some retinal diseases. Depending on your condition, treatment goals may be to stop or slow the disease and preserve, improve or restore your vision. Untreated, some retinal diseases can cause severe vision loss or blindness.

Types

Common retinal diseases and conditions include:

  • Retinal tear. A retinal tear occurs when the clear, gel-like substance in the center of your eye (vitreous) shrinks and tugs on the thin layer of tissue lining the back of your eye (retina) with enough traction to cause a break in the tissue. It's often accompanied by the sudden onset of symptoms such as floaters and flashing lights.
  • Retinal detachment. A retinal detachment is defined by the presence of fluid under the retina. This usually occurs when fluid passes through a retinal tear, causing the retina to lift away from the underlying tissue layers.
  • Diabetic retinopathy. If you have diabetes, the tiny blood vessels (capillaries) in the back of your eye can deteriorate and leak fluid into and under the retina. This causes the retina to swell, which may blur or distort your vision. Or you may develop new, abnormal capillaries that break and bleed. This also worsens your vision.
  • Epiretinal membrane. Epiretinal membrane is a delicate tissue-like scar or membrane that looks like crinkled cellophane lying on top of the retina. This membrane pulls up on the retina, which distorts your vision. Objects may appear blurred or crooked.
  • Macular hole. A macular hole is a small defect in the center of the retina at the back of your eye (macula). The hole may develop from abnormal traction between the retina and the vitreous, or it may follow an injury to the eye.
  • Macular degeneration. In macular degeneration, the center of your retina begins to deteriorate. This causes symptoms such as blurred central vision or a blind spot in the center of the visual field. There are two types — wet macular degeneration and dry macular degeneration. Many people will first have the dry form, which can progress to the wet form in one or both eyes.
  • Retinitis pigmentosa. Retinitis pigmentosa is an inherited degenerative disease. It slowly affects the retina and causes loss of night and side vision.
Parts of the inner eye

The macula is located at the back of the eye in the center of the retina. A healthy macula allows for clear central vision. The macula is made up of densely packed light-sensitive cells called cones and rods. Cones give the eye color vision, and rods let the eye see shades of gray.

Symptoms

Many retinal diseases share some common signs and symptoms. These may include:

  • Seeing floating specks or cobwebs
  • Blurred or distorted (straight lines look wavy) vision
  • Defects in the side vision
  • Lost vision

You may need to try looking with each eye alone to notice these.

When to see a doctor

It's important to pay attention to any changes in your vision and find care quickly. Seek immediate medical attention if you suddenly have floaters, flashes or reduced vision. These are warning signs of potentially serious retinal disease.

Risk factors

Risk factors for retinal diseases might include:

  • Aging
  • Smoking
  • Being obese
  • Having diabetes or other diseases
  • Eye trauma
  • A family history of retinal diseases

Diagnosis

To make a diagnosis, your ophthalmologist conducts a thorough eye exam and looks for abnormalities anywhere in the eye.

The following tests may be done to determine the location and extent of the disease:

  • Amsler grid test. Your doctor may use an Amsler grid to test the clarity of your central vision. He or she will ask you if the lines of the grid seem faded, broken or distorted and will note where the distortion occurs on the grid to better understand the extent of retinal damage. If you have macular degeneration, he or she might also ask you to use this test to self-monitor your condition at home.
  • Optical coherence tomography (OCT). This test is an excellent technique for capturing precise images of the retina to diagnose epiretinal membranes, macular holes and macular swelling (edema), to monitor the extent of age-related wet macular degeneration, and to monitor responses to treatment.
  • Fundus autofluorescence (FAF). FAF may be used to determine the advancement of retinal diseases, including macular degeneration. FAF highlights a retinal pigment (lipofuscin) that increases with retinal damage or dysfunction.
  • Fluorescein angiography. This test uses a dye that causes blood vessels in the retina to stand out under a special light. This helps to exactly identify closed blood vessels, leaking blood vessels, new abnormal blood vessels and subtle changes in the back of the eye.
  • Indocyanine green angiography. This test uses a dye that lights up when exposed to infrared light. The resulting images show retinal blood vessels and the deeper, harder-to-see blood vessels behind the retina in a tissue called the choroid.
  • Ultrasound. This test uses high-frequency sound waves (ultrasonography) to help view the retina and other structures in the eye. It can also identify certain tissue characteristics that can help in the diagnosis and treatment of eye tumors.
  • CT and MRI. In rare instances, these imaging methods can be used to help evaluate eye injuries or tumors.

Treatment

The main goals of treatment are to stop or slow disease progression and preserve, improve or restore your vision. In many cases, damage that has already occurred can't be reversed, making early detection important. Your doctor will work with you to determine the best treatment.

Treatment of retinal disease may be complex and sometimes urgent. Options include:

  • Using a laser. Laser surgery can repair a retinal tear or hole. Your surgeon uses a laser to heat small pinpoints on the retina. This creates scarring that usually binds (welds) the retina to the underlying tissue. Immediate laser treatment of a new retinal tear can decrease the chance of it causing a retinal detachment.
  • Shrinking abnormal blood vessels. Your doctor may use a technique called scatter laser photocoagulation to shrink abnormal new blood vessels that are bleeding or threatening to bleed into the eye. This treatment may help people with diabetic retinopathy. Extensive use of this treatment may cause the loss of some side (peripheral) or night vision.
  • Freezing. In this process, called cryopexy (KRY-o-pek-see), your surgeon applies a freezing probe to the external wall of the eye to treat a retinal tear. Intense cold reaches the inside of the eye and freezes the retina. The treated area will later scar and secure the retina to the eye wall.
  • Injecting air or gas into your eye. This technique, called pneumatic retinopexy (RET-ih-no-pek-see), is used to help repair certain types of retinal detachment. It can be used in combination with cryopexy or laser photocoagulation.
  • Indenting the surface of your eye. This surgery, called scleral (SKLAIR-ul) buckling, is used to repair a retinal detachment. Your surgeon sews a small piece of silicone material to the outside eye surface (sclera). This indents the sclera and relieves some of the force caused by the vitreous tugging on the retina and reattaches the retina. This technique may be used with other treatments.

  • Evacuating and replacing the fluid in the eye. In this procedure, called vitrectomy (vih-TREK-tuh-me), your surgeon removes the gel-like fluid that fills the inside of your eye (vitreous). He or she then injects air, gas or liquid into the space.

    Vitrectomy may be used if bleeding or inflammation clouds the vitreous and obstructs the surgeon's view of the retina. This technique may be part of the treatment for people with a retinal tear, diabetic retinopathy, a macular hole, epiretinal membrane, an infection, eye trauma or a retinal detachment.

  • Injecting medicine into the eye. Your doctor may suggest injecting medication into the vitreous in the eye. This technique may be effective in treating people with wet macular degeneration, diabetic retinopathy or broken blood vessels within the eye.
  • Implanting a retinal prosthesis. People who have severe vision loss or blindness owing to certain inherited retinal disease may need surgery. A tiny electrode chip is implanted in the retina that receives input from a video camera on a pair of eyeglasses. The electrode picks up and relays visual information that the damaged retina can no longer process.
A scleral buckle used to treat retinal detachment

Silicone material stitched to the outside of the eye indents (buckles) the sclera, causing a slight decrease in the circumference of the eye. A scleral buckle is sometimes used in the management of retinal detachment.

Coping and support

Vision loss from retinal disease can affect your ability to do things such as read, recognize faces and drive. These tips may help you cope with your changing vision:

  • Ask your eye doctor to check your eyeglasses. If you wear contacts or glasses, be sure your prescription is up to date and at maximum strength. If a stronger pair of glasses doesn't help, ask for a referral to a low-vision specialist.
  • Use prescribed magnifiers. A variety of magnifying devices prescribed by a low-vision specialist can help you with reading and close-up work, such as sewing. Such devices include hand-held lenses or magnifying lenses you wear like glasses. You may also use a closed-circuit television system that uses a video camera to magnify reading material and project it on a video screen. Over-the-counter magnifiers may not work as well.
  • Change your computer display and add audio systems. Adjust the font size and monitor contrast in your computer's settings. Consider adding speech-output systems or other technologies to your computer.
  • Use electronic reading aids and voice interface. Try talking watches, clocks and calculators, large-print books, tablet computers, and audio books. Some tablet and smartphone apps are designed to help people with low vision. And many of these devices now come with a voice recognition feature.
  • Select special appliances made for low vision. Some clocks, radios, telephones and other appliances have extra-large numbers. You may find it easier to watch a television with a larger high-definition screen, or you may want to sit closer to the screen.
  • Use brighter lights in your home. Better lighting helps with reading and other daily activities, and it may also reduce the risk of falling.
  • Consider your transportation options. If you drive, check with your doctor to see if it's safe to continue doing so. Be extra cautious in certain situations, such as driving at night, in heavy traffic or in bad weather. Use public transportation or ask a friend or family member to help. Make arrangements to use local van or shuttle services, volunteer driving networks, or ride-shares.
  • Get support. Having a retinal condition can be difficult, and you may need to make changes in your life. You may go through many emotions as you adjust. Consider talking to a counselor or joining a support group. Spend time with supportive family members and friends.

Preparing for an appointment

To check for retinal disease, a dilated eye exam is usually necessary. Make an appointment with a doctor who specializes in eye care — an optometrist or an ophthalmologist. He or she can perform a complete eye exam.

What you can do

Before your appointment:

  • When you make the appointment, ask if you need to do anything to prepare.
  • List any symptoms you're experiencing, including those that seem unrelated to your vision problem.
  • List all medications, vitamins and supplements you take, including doses.
  • Ask a family member or friend to accompany you. Having your pupils dilated for the eye exam will affect your vision for a time afterward, so you may need someone to drive or accompany you after your appointment.
  • List questions to ask your doctor.

For retinal disease, questions to ask your doctor include:

  • How advanced is my condition?
  • Is it safe for me to drive?
  • Will I experience further vision loss?
  • Can my condition be treated?
  • Will taking a vitamin or mineral supplement help prevent further vision loss?
  • What's the best way to monitor my vision for any changes?
  • What changes in my symptoms warrant calling you?
  • What low-vision aids might be helpful to me?
  • What lifestyle changes can I make to protect my vision?

What to expect from your doctor

Your doctor is likely to ask you a number of questions, such as:

  • When did you first notice your vision problem?
  • Does the condition affect one or both eyes?
  • Do you have trouble seeing things near you, at a distance or both?
  • Do you smoke or did you ever smoke? If so, how much?
  • Do you have other medical problems, such as high cholesterol, high blood pressure or diabetes?
  • Do you have a family history of retinal disease?
  • Have you experienced an injury to your eye?

Last Updated Jan 6, 2022

© 2024 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. Terms of Use

Explore Our Learning Center